diff --git a/setup.py b/setup.py
index 1f4838c..a809328 100644
--- a/setup.py
+++ b/setup.py
@@ -54,23 +54,6 @@ install_requires = [
     'zope.interface',
 ]
 
-# Add pywin32 on Windows platforms to handle low-level system calls.
-# This dependency needs to be added using environment markers to avoid its installation on Linux.
-# However environment markers are supported only with setuptools >= 36.2.
-# So this dependency is not added for old Linux distributions with old setuptools,
-# in order to allow these systems to build certbot from sources.
-pywin32_req = 'pywin32>=224'
-if StrictVersion(setuptools_version) >= StrictVersion('36.2'):
-    install_requires.append(pywin32_req + " ; sys_platform == 'win32'")
-elif 'bdist_wheel' in sys.argv[1:]:
-    raise RuntimeError('Error, you are trying to build certbot wheels using an old version '
-                       'of setuptools. Version 36.2+ of setuptools is required.')
-elif os.name == 'nt':
-    # This branch exists to improve this package's behavior on Windows. Without
-    # it, if the sdist is installed on Windows with an old version of
-    # setuptools, pywin32 will not be specified as a dependency.
-    install_requires.append(pywin32_req)
-
 dev_extras = [
     'astroid==1.6.5',
     'coverage',